SYNERA^® (70 mg lidocaine/ 70 mg tetracaine) topical patch should not be used by patients with sensitivity to lidocaine, tetracaine, or any other component of the product. SYNERA^® should also not be used in patients who have a para-aminobenzoic acid (PABA) sensitivity.

In clinical studies, some skin reactions occurred at the application site, including redness, blanching, and swelling. These reactions were generally mild and went away by themselves.

Allergic reactions such as hives, difficulty breathing, skin redness or swelling, and shock can occur. Notify your healthcare provider immediately if you notice any of these or other symptoms.

SYNERA^® numbs the skin. Do not rub, scratch, or expose the treated area to heat or cold before complete sensation returns.

Even a used patch contains a large amount of lidocaine and tetracaine. A child or pet could suffer adverse effects from chewing or swallowing a new or used SYNERA^® patch. Store and dispose patches out of their reach.

Not for home use by patient.

To learn more about SYNERA^®, contact your healthcare provider or call 1-866-949-9277.

Please see accompanying full Prescribing Information